在E10.5胚胎提取物中,通过Northern blot分析确认了不含转录表达的lacZ基因,它带有核定位信号和5'的lox71位点,接着是neo cassette,被lox2272序列包裹。Mirn214的转录表达未检测到,而Mirn199a-2的表达则有所下调。(来源:J:143209)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x 129)F1
Targeted
插入,基因内删除
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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