这项突变是在一个ENU诱变雄性小鼠的G3后代中发现的,它位于13号染色体,从着丝粒到D13Mit14区域,该区域包含了Lyst基因。对突变小鼠中Lyst基因90%的序列分析并未发现突变。然而,在补救测试中,这项突变被确认与beige Beutler(Lystbg-Btlr)是等位基因,Lyst基因在后者中已知有变异。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
未定义
隐性
1
2
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部