这个Pcdh-gamma的靶向载体被设计成在gamma-protocadherin(帕金森病相关δ钙黏素,Pcdh-gamma)的恒定exon 3上游插入一个LoxP位点,然后连接一个由LoxP标记的PGK-neomycin抗性基因 cassette(Neo)。(来源:J:142186)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count