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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(tetO-Nfatct1*)1Grc
Alias:
NFATc1
nuc
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基础信息
表型特征
文献报道
CMV启动子与四环素响应元件相连,用于驱动四环素调控的、普遍表达的修改过的Nfatc1基因,该基因编码一个核定位的蛋白质,因为其核苷酸变异导致替换了正常由钙调素去磷酸化的丝氨酸为异亮氨酸。没有提供细胞系信息,来源为(J:109543)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3820649
(C57BL/6J x CBA/J)F1
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7
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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