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中文
膜周边区域被替换为编码一种可翻转诺卡因抗性基因的DNA，该基因的7个氨基酸(APVVPTR)来自于小鼠的选择素(Eng)。预测这种突变会阻止细胞激活时蛋白质的剪切。通过流式细胞术分析，发现突变蛋白在纯合子血液、脾脏和淋巴细胞表面的表达量分别只有对照野生型的27%、34%和52%。淋巴细胞在激活状态下，突变蛋白并未从细胞表面被剪切下来。(来源：J:142184)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
