4号和5号外显子被替换了新插入的neo cassette。通过Friend病毒感染的红细胞提取物的 Western blot 分析,证实了没有蛋白质表达(来源:J:141545)
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Exons 4 and 5 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on Friend virus-infected erythroid cell extracts. (J:141545)