将NM_027144基因的第一个编码外显子(8-307核苷酸位置)和部分5' UTR替换为neo cassette。通过在肝脏和其它组织的 Western blot 分析,证实了没有蛋白质表达(来源:J:141641)。
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The first coding exon (nucleotides 8-307 of NM_027144) and part of the 5' UTR were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on liver and other organ extracts. (J:141641)