Luzp1^tm1Acch

A NcoI-NcoI fragment at the upstream portion of the open reading frame was replaced with an in-frame LacZ-hprt reporter gene. Gene inactivation was confirmed by a lack of protein found on immunoblotting of brain extracts from E12.5 homozygotes. LacZ expression was detected in the neuroepithelium and mysenchymal cells of both the forebrain and hindbrain of E9 homozygote embryos. (J:141306, J:283453)