在第1外显子被替换为编码"Flag-HA"抗原标签的修改版本,该标签位于基因产物的氨基端。下游位置插入了一个floxed Neo抗药性基因座。通过Cre重组酶的暂时表达,删除了Neo基因座。通过抗HA抗体的免疫印迹试验确认了蛋白表达。(来源:J:141142)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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