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中文
Exon 1，包含ATG启动子的部分，被替换了抗氨苄青霉素抗性基因座。Southern blot结果显示ES细胞靶向正确。对杂合子肝脏提取物的免疫印迹分析显示，蛋白质表达减少了超过一半，这证实了基因功能失活。（来源：J:140627）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
