插入了Velocigene cassette ZEN-Ub1导致染色体19(建库GRCm39)上4889494-4892116位点间删除了2623bp。单一外显子被LacZ报告基因 cassette替换,随后跟着诺卡因抗性 cassette。 Western blot结果显示,纯合突变小鼠睾丸和附睾精子中未检测到蛋白表达。(来源:J:136110, J:265624)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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