在包含起始翻译序列的exon 1被替换成带有FRT标签的可诱导删除的exon 1和一个上游的诺卡因抗性基因座。在通过靶向后通过FLP重组酶的生殖细胞表达下,诺卡因抗性基因座会被剔除。当表达cre重组酶时,exon 1会被剪切,形成无功能等位基因。(来源:J:140109)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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