这个转基因构建包含了人类SNCA(α-synuclein)基因的A53T突变形式,由人THY1(胸腺细胞抗原1, theta)启动子控制。在大脑中,转基因的表达增加了10倍,而在脊髓中则增加了20倍。(来源:J:140019)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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