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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gpx4
tm2.1Marc
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基础信息
表型特征
文献报道
携带Gpx4tm2Marc基因突变的鼠与携带Tg(Camk2a-cre)2Gsc转基因鼠杂交,目的是在后代中剔除5-7号染色体上的基因片段。基因片段缺失通过Southern blot技术得到了确认。(来源:J:139668)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3810784
129P2/OlaHsd
Targeted
基因内删除
--
1
1
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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