在exon 11的上游插入了loxP位点,然后在exon 15的3'端插入了含frt标签的neo cassette,它自身带有loxP位点。通过小鼠的生殖细胞中使用flp介导的重组,移除了neo cassette,使得exons 11到15都被留下了loxP标记。(来源:J:139510)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
插入
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1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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