pGT1Lxf基因捕获载体插入了第9号外显子。Northern blot分析在杂合纤维细胞中检测到了野生型转录本和一个较大的融合转录本。通过免疫荧光,在PMEFs中检测到了由核质端氨基酸区和前四个跨膜域与β-geo融合形成的融合多肽。(来源:J:138854)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
基因捕获载体的插入
--
1
6
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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