Lbr^Gt(XE569)Byg

The pGT1Lxf gene trap vector inserted into exon 9. Northern blot analysis detects a larger fusion transcript in addition to the wild-type transcript in heterozygous fibroblasts. A fusion polypeptide consisting of the amino terminal nucleoplasmic domain and first four transmembrane domains fused to beta-geo is detected by immunofluorescence in PMEFs. (J:138854)