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中文
在exon 10的最后一个三联体C端PDZ结合区，通过同源重组用alanine密码子替换了原有的密码子。同时，插入了一个可删除的neo cassette，随后通过Cre介导的重组在ES细胞中移除。 Western blot结果显示，纯合子和杂合子小鼠大脑中的蛋白质表达量分别减少了约35%和15%。(来源：J:138831)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
