这个基因被敲入到了位点,它缺失编码TRAF3结合区的序列,前面有一个floxed neo STOP cassette,后面跟着一个frt-flanked IRES-EGFP cassette,表达是通过Cre诱导的,且是普遍性的。为了得到表达,需要Cre介导去除STOP cassette。(来源:J:139293, J:157820)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
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10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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