这个基因被敲入到了位点,它缺失编码TRAF3结合区的序列,前面有一个floxed neo STOP cassette,后面跟着一个frt-flanked IRES-EGFP cassette,表达是通过Cre诱导的,且是普遍性的。为了得到表达,需要Cre介导去除STOP cassette。(来源:J:139293, J:157820)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count