Tradd^tm1.1Mak

Mice containing the Traddtm1Mak allele were crossed with Cre-deleter mice to excise exons 3-5 that encode the functional "death domain" of the gene product. Gene inactivation was confirmed by a lack of protein product as determined by western blotting of embryonic fibroblasts from homozygote mice. (J:138824)