在第6外显子3'端插入了一个含puromycin抗性基因、Hprt小片段基因和agouti小片段基因的盒式DNA。插入后,3-6号外显子发生了复制。Northern blot结果显示,这种等位基因在肝脏RNA中完全没有转录出的mRNA。(来源:J:138734)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
2
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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