通过将具有第一编码外显子敲除的Fmr1小鼠与在生殖细胞中表达Cre重组酶的 mice (Tg(CAG-cre)13Miya) 杂交,创造出了一个生殖细胞的隐性突变。基因失活通过免疫印迹分析在大脑和睾丸中缺乏蛋白质表达来验证。(来源:J:108008)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
基因内删除
--
1
5
47

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部