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中文
通过同源重组，对exon 2的编码序列进行了定点突变，产生了甘氨酸(343位)和异亮氨酸(344位)的替换，分别替换为苯丙氨酸(替换为F343G和F344A)。这种变异影响了蛋白质相互作用中的两个关键氨基酸。在exon 2下游，还插入了一个neo cassette用于选择性标记。(来源：J:138901)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
