插入了Velocigene cassette ZEN-Ub1导致了4号染色体(GRCm39构建)上6,326,2838-6,328,4003位置之间21,166bp的缺失。Orm1、Orm2和Orm3基因据信紧密连锁,这条小鼠线上的这三个基因都会被消除。在肝脏中,未检测到Orm1、Orm2和Orm3的mRNA(文献引用:J:136110, J:292194)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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