在7号染色体上,胰岛素2基因的下游2.6kb位置,且与7号染色体 imprinting中心1(H19 DMR)和中心2(KvDMR1)的影响力区域同向,插入了一个仅由磷化酶激酶启动子驱动的诺韦罗康抗性 cassette,其被两个loxP序列 flank(loxP-PGK-loxP-neo-pA)。(来源:J:130399)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
9
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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