Myh6启动子被用来驱动心脏特异性的Tnnt2 cDNA表达,其中包含导致第210位lysine缺失的核苷酸突变。这种突变模仿了扩张型心肌病患者中发现的突变。四条 lines 产生了类似的表现型,但没有给出具体line numbers。(来源:J:137964)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count