Myh6启动子被用来驱动心脏特异性的Tnnt2 cDNA表达,其中包含导致第210位lysine缺失的核苷酸突变。这种突变模仿了扩张型心肌病患者中发现的突变。四条 lines 产生了类似的表现型,但没有给出具体line numbers。(来源:J:137964)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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