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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Del(7Ifitm5-Ifitm6)1Masu
Alias:
IfitmDel
Del1Masu
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基础信息
表型特征
文献报道
使用MICE载体插入了loxP位点,一个位于Ifitm5基因的着丝粒区,另一个位于Ifitm6基因的端粒区。在胚胎干细胞中短暂表达Cre,以去除这两基因之间大约120kb的基因组区域,包括Ifitm5、Ifitm2、Ifitm1、Ifitm3和Ifitm6。(来源:J:137940)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3804041
129P2/OlaHsd
Targeted
Intergenic deletion, Intragenic deletion
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7
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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