Exon 1,包含转录起始密码子的部分,被替换了带有floxed neo cassette。蛋白质产物的缺失通过免疫组化和 Western blot 实验得到了确认(来源:J:137841)
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Exon 1, that contains the transcription initiation codon, was replaced by a floxed neo cassette. The absence of protein product was confirmed by immunohistochemistry and western blot analysis. (J:137841)