这个转基因包含了小鼠乳清酸蛋白(Wap)启动子的4.5kb基因片段,后面跟着兔β-珠蛋白的内含子,Cre编码序列,以及人类生长激素基因的转录终止/polyadenylation片段。经过纯化的7.8kb片段,被注入了FVB/N小鼠的囊胚阶段胚胎中。这是一条表达量较低的品系(15,来源:J:171765)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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插入
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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