在CE5外显子上游插入了loxP位点,接着在CE5后方插入了一个带有3' loxP座的frt-flankedneo cassette。通过遗传背景的germ line,利用flp介导的重组来去除neo cassette,使得CE5外显子被标记为可删除的。(来源:J:137217)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count