12号和13号外显子被替换了新插入的neo cassette。通过淋巴结和脾脏提取物的 Western blot 分析,证实了没有完整蛋白产生,存在一个截短蛋白产物。(来源:J:137269)
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Exons 12 and 13 were replaced with a neo cassette. The absence of full-length protein and the presence of a truncated protein product was confirmed by western blot analysis on lymph node and spleen extracts. (J:137269)