在exon 2的上游插入了lox P座,然后在exon 4的下游插入了一个带有5' loxP座的frt-flanked neo cassette。通过遗传背景的germ line,使用flp介导的重组来去除neo cassette,使得exons 2到4都被留下了lox P标记。(来源:J:136451)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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