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一个核苷酸转换导致密码子从TTC变为ATC，从而在第268位氨基酸位置由苯丙氨酸替换为异亮氨酸(替换为I268F)。为了筛选目的，一个带有floxed neo cassette的neo cassette通过小鼠的生殖细胞经Cre介导的重组被去除了(来源：J:137156)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
