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在第一个编码外显子上游插入了loxP位点，然后在该外显子下游插入了一个带有3' loxP座的frt标记的neo cassette。通过转基因小鼠的germ line，使用flp介导的重组来消除neo cassette，使得第一个编码外显子被去除了(来源：J:136388)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
