在exon 2上游插入了一个floxed neo cassette,然后在exon 2下游插入了一个loxP位点。通过小鼠的生殖细胞(germ line)中cre介导的重组,移除了neo cassette,使得exon 2被留了下来。(来源:J:136670)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count