Exon 2被替换成lacZ/neo插入片段。通过 Western blot 分析确认了没有蛋白质产物产生。这是一项无蛋白产生基因(Null allele)和报告基因(Reporter allele)。(来源:J:136558)
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Exon 2 was replaced with a lacZ/neo cassette. The absence of protein product was confirmed by western blot analysis. This is a null allele and a reporter allele. (J:136558)