在第21外显子上游插入了loxP位点,然后在第22外显子下游插入了带有5' loxP位点的frt-flanked neo cassette。通过基因组的germ line中使用flp介导的重组,移除了neo cassette,使得第21和22外显子被标记为可剪接。来源:(J:136305)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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