这个转基因包含12.3千碱基的人类基因组DNA,包含GPD1基因,包括3.5千碱基的5'上游序列,7.6千碱基的编码区和1.2千碱基的3'下游DNA。5'上游序列包括了近端和远端的启动子区域。A1创始株大约有6个拷贝的转基因。小鼠在大脑皮层的转基因表达水平远高于内源基因的正常水平。(来源:J:135002)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x LT/Sv)F1
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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