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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(PON1)1Lus
Alias:
PON1 Tg
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基础信息
表型特征
文献报道
使用含有完整人类PON1基因的45kb片段,包括5'端10kb的上游序列和3'端10kb的下游序列,来进行Tg小鼠的制备。这个转基因小鼠品系通过Southern blot分析显示,携带了大约3个拷贝的转基因。(来源:J:103311)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3795158
C57BL/6J
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1
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7
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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