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在4号和5号外显子之间插入了loxP位点。下游的Neomycin抗性基因座在8号外显子之后被插入，并取代了Tbx6基因的最后4个氨基酸编码。通过Cre介导的重组，选择性座点被去除了。北半球印迹分析证实了胚胎中Ppp4c转录本的正常表达。RT-PCR确认了Tbx6转录本的正常表达。同样，Cre介导的重组移除了选择性座点。（来源：J:134682）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
