germ line(生殖线)中,通过cre介导的重组去除了exon 7。通过在cre介导重组后重建该等位基因的鼠胚胎成纤维细胞提取物中进行 Western blot 分析,证实了这个等位基因无蛋白产物产生。(来源:J:134665)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
基因内删除
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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