Mir106a、Mir18b、Mir20b、Mir19b-2、Mir92-2和Mir363基因被替换成一个Frt标记的诺卡因筛选 cassette。靶向载体被导入V6.5背景的C57BL/6 x 129S4/SvJae杂交胚胎干细胞(ES)。诺卡因 cassette通过Flp介导的剔除被去除。(来源:J:134861)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
基因间区删除
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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