Exon 3被替换成一个带有IRES-lacZ-neo插件的序列。通过 hippocampus组织的 Western blot 分析,确认了没有蛋白质产物产生。这是一项无功能等位基因和报告基因(来源:J:134800)。
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Exon 3 was replaced with an IRES-lacZ-neo cassette. The absence of protein product was confirmed by western blot analysis on hippocampus extracts. This is a null allele and a reporter allele. (J:134800)