In(10)17Rk

This triethylene melamine-induced inversion of approximately 60 cM causes a homozygous pygmy phenotype, it is allelic by complementation test with Hmga2pg, the distal breakpoint is in intron 3 of Hmga2, and the proximal breakpoint is in intron 2 of Txlnb. A 3.7 kb fusion transcript of Hmga2 exons 4 and 5 and Txlnb exons 1 and 2 is produced. No other Txlnb transcript was found by northern blot of homozygous heart or femur. (J:28571, J:43743, J:74548)