Exon 3被替换成lacZ载体。通过热提取物的 Western blot 分析确认了没有蛋白质产物产生。这是一项无蛋白基因(Null allele)和报告基因(Reporter allele)。(来源:J:133708)
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Exon 3 was replaced with a lacZ cassette. The absence of protein product was confirmed by western blot analysis on heat extracts. This is a null allele and a reporter allele. (J:133708)