将完整的mouse Ighmbp2 cDNA序列插入到一个修改后的5.87kb小鼠基因组片段中,该片段包含了Ttn启动子、非编码的Ttn exon 1、内含子1和Ttn exon 2的30bp缺失起始密码子区域。转基因表达仅限于心脏和骨骼肌肉,通过RT-PCR检测Ighmbp2 exon 1确认了这一点(来源:J:102748)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
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插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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