Exon 17被替换成一个β-geo基因捕获载体。通过脑和坐骨神经提取物的 Western blot 分析,确认了没有蛋白质产物产生。这是一项无功能性基因(来源:J:133391)
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Exon 17 was replaced by a beta-geo gene trap vector. The absence of protein product was confirmed by western blot analysis on brain and sciatic nerve extracts. This is a null allele. (J:133391)