在编码经典G-1GTP酶模体的第四外显子前,插入了FRT引导的neo cassette,后面跟着两个loxP位点,然后替换掉了原有的基因座。通过与表达FLP重组酶的小鼠杂交,移除了neo cassette(来源:J:132329)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
--
40

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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