在内皮1中的近端SF-1结合位点被替换为遗传序列从TAGCCTTGA变为TAGaaTTGA的位点。在内皮1中插入了一个带有3' lox P座的删除型neo cassette,但通过小鼠的生殖细胞基因组重组被去除了。该蛋白质产物在肾上腺和睾丸中的表达减少了7倍,而在胎盘和卵巢中则没有影响。(来源:J:133007)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Nucleotide substitutions
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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