Atp7a^Mo-Btlr

The tigrou-like mutation corresponds to a C-to-T transition at nucleotide position 3073, in exon 15 of 23 total exons, that results in replacement of alanine by valine at amino acid 999 of the protein. This is in the highly conserved sixth transmembrane domain that participates in formation of the cation channel. (J:133115, J:188598)