将cre重组酶编码序列、SV40polyadenylation信号后接frt座标记的PGK-neo选择座(反向插入),通过TT2胚胎干细胞中Nanos3基因的同源重组插入到exon1。在胚胎期7.75日时,这种表达在生殖细胞中迁移阶段和进入生殖腺后被检测到。(来源:J:136687)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count