将cre重组酶编码序列、SV40polyadenylation信号后接frt座标记的PGK-neo选择座(反向插入),通过TT2胚胎干细胞中Nanos3基因的同源重组插入到exon1。在胚胎期7.75日时,这种表达在生殖细胞中迁移阶段和进入生殖腺后被检测到。(来源:J:136687)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
插入
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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